Optimal tentative abdominal closure for open abdomen: a multicenter retrospective observational study (OPTITAC study).

ABSTRACT:

Background

Primary fascia closure is often difficult following an open abdomen (OA). While negative-pressure wound therapy (NPWT) is recommended to enhance successful primary fascia closure, the optimal methods and degree of negative pressure remain unclear. This study aimed to elucidate optimal methods of NPWT as a tentative abdominal closure for OA to achieve primary abdominal fascia closure.

Materials and methods

A multicenter, retrospective, cohort study of adults who survived OA greater than 48 h was conducted in 12 institutions between 2010 and 2022. The achievement of primary fascia closure and incidence of enteroatmospheric fistula were examined based on methods (homemade, superficial NPWT kit, or open-abdomen kit) or degrees of negative pressure (<50, 50-100, or >10

SUBMITTER: Yamamoto R 

PROVIDER: S-EPMC10720862 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature