Clinicopathological features and prognosis of synchronous and metachronous colorectal cancer: a retrospective cohort study.

ABSTRACT:

Background

To investigate the clinicopathological features and prognosis of synchronous and metachronous multiple primary colorectal cancer.

Materials and methods

Patients who underwent operation for synchronous and metachronous colorectal cancer at the colorectal surgery department of XX Hospital between January 2000 and December 2021 were included. Perioperative indicators were comprehensively compared and included in the survival analyses.

Results

In total, 563 patients with synchronous (n=372) and metachronous (n=191) colorectal cancer were included. Patients with synchronous colorectal cancer were more likely to have a long onset time, positive carcinoembryonic antigen, advanced TNM stage, large tumor, perineural invasion, p53 high expression, and mismatch repair

SUBMITTER: Fan H 

PROVIDER: S-EPMC10720868 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature