Circulating intermediate monocytes CD14++CD16+ are increased after elective percutaneous coronary intervention.

ABSTRACT:

Aim

Inflammation plays a central role in the pathogenesis of atherosclerosis and in the sequelae of percutaneous coronary intervention (PCI). Previous work demonstrated that intermediate monocytes (CD14++CD16+) are associated with adverse cardiovascular events, yet monocyte subset response following elective PCI has not been described. This article explores the changes in monocyte subset and humoral response after elective PCI.

Methods

This prospective study included 30 patients without inflammatory diseases being referred for elective PCI. We included patients treated with drug coated balloons or 2nd generation drug eluting stents. Patients underwent blood tests at baseline (prior to PCI), four hours, two weeks and two months later. Analyses were performed in terms of monoc

SUBMITTER: Merinopoulos I 

PROVIDER: S-EPMC10721025 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature