Ontology highlight
ABSTRACT:
SUBMITTER: Yamada K
PROVIDER: S-EPMC10721602 | biostudies-literature | 2023 Dec
REPOSITORIES: biostudies-literature
Yamada Kohdai K Shioya Ryouhei R Nishino Kohei K Furihata Hirotake H Hijikata Atsushi A Kaneko Mika K MK Kato Yukinari Y Shirai Tsuyoshi T Kosako Hidetaka H Sawasaki Tatsuya T
Nature communications 20231214 1
Receptor proteins, such as epidermal growth factor receptor (EGFR), interact with other proteins in the extracellular region of the cell membrane to drive intracellular signalling. Therefore, analysis of extracellular protein-protein interactions (exPPIs) is important for understanding the biological function of receptor proteins. Here, we present an approach using a proximity biotinylation enzyme (AirID) fusion fragment of antigen binding (FabID) to analyse the proximity exPPIs of EGFR. AirID w ...[more]