Effect of serum autoantibodies on the COVID-19 patient's prognosis.

ABSTRACT:

Objectives

Virus infection closely associated with autoimmune disease. The study aimed to explore the autoantibody profiles and the correlation of autoantibodies with the disease severity and the prognosis of the coronavirus disease 2019 (COVID-19) patients.

Methods

Three hundred thirty-seven hospitalized COVID-19 patients from 6th to 23rd January 2023 were enrolled. Logistic and Cox regression analyses were used to analyze the risk factors for the patient's disease severity and outcome. The association between Anti-extractable nuclear antigen antibody (ENA) positivity and the prognosis of COVID-19 patients was analyzed using Kaplan-Meier survival curves.

Results

137 of COVID-19 patients were detected positive for antinuclear antibody (ANA), 61 had positive results fo

SUBMITTER: Zhang W 

PROVIDER: S-EPMC10721969 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature