Dataset Information

Aesthetic Enhancement of the Gonial Angle and Inferior Mandibular Border in the Chinese Population.

ABSTRACT:

Background

The current absence of a standardized mandibular body osteotomy design poses challenges in surgical planning. Traditional approaches may not suit patients with wider anterior mandibles, potentially resulting in unsatisfactory outcomes. Addressing this issue requires a rational design that combines mandibular angle and body osteotomies for improved clinical practice.

Objectives

This retrospective cohort study aimed to analyze mandibular computed tomography (CT) data using digital methods. The goal was to establish an integrated osteotomy design for both mandibular angle and body procedures and classify prevalent mandibular types in the Chinese Han population for surgical guidance.

Methods

Included were 89 patients who underwent mandibular angle osteotomy without genioplasty between 2016 and 2022 at Peking University Third Hospital. Mimics 21.0 software (Materialise; Leuven, Belgium) facilitated CT data reconstruction and osteotomy planning. Postoperative effects were assessed through imaging, complications, and surveys, leading to mandibular type classification.

Results

Mandibular angles were categorized into three types based on osteotomy range. Type I involved mandibular body osteotomy only, Type II mandibular angle osteotomy only, and Type III both mandibular angle and body osteotomies. Distribution within the cohort was 2.25%, 8.99%, and 88.76% for Types I, II, and III respectively. Patient satisfaction was high, with minor and major complications at 47.19% and 1.12% using Clavien-Dindo classification.

Conclusions

Utilizing Mimics software, this study established an integrated osteotomy design and categorized mandibular types. Findings offer valuable guidance for mandibular angle surgery and contribute to Asian mandibular morphology understanding.

SUBMITTER: Zhang C

PROVIDER: S-EPMC10722113 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature

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Publications

Aesthetic Enhancement of the Gonial Angle and Inferior Mandibular Border in the Chinese Population.

Zhang Chen C Shi Yurui Y Du Shanshan S Bi Hongsen H

Aesthetic surgery journal 20231201 1

<h4>Background</h4>The current absence of a standardized mandibular body osteotomy design poses challenges in surgical planning. Traditional approaches may not suit patients with wider anterior mandibles, potentially resulting in unsatisfactory outcomes. Addressing this issue requires a rational design that combines mandibular angle and body osteotomies for improved clinical practice.<h4>Objectives</h4>In this retrospective cohort study we aimed to analyze mandibular computed tomography (CT) dat ...[more]

PMID: 37757894

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Project description:Tissue engineering has become a new approach for repairing bony defects. Highly porous osteoconductive scaffolds perform the important role for the success of bone regeneration. By biomimetic strategy, apatite-coated porous biomaterial based on silk fibroin scaffolds (SS) might provide an enhanced osteogenic environment for bone-related outcomes. To assess the effects of apatite-coated silk fibroin (mSS) biomaterials for bone healing as a tissue engineered bony scaffold, we explored a tissue engineered bony graft using mSS seeded with osteogenically induced autologous bone marrow stromal cells (bMSCs) to repair inferior mandibular border defects in a canine model. The results were compared with those treated with bMSCs/SS constructs, mSS alone, SS alone, autologous mandibular grafts and untreated blank defects. According to radiographic and histological examination, new bone formation was observed from 4 weeks post-operation, and the defect site was completely repaired after 12 months for the bMSCs/mSS group. In the bMSCs/SS group, new bone formation was observed with more residual silk scaffold remaining at the center of the defect compared with the bMSCs/mSS group. The engineered bone with bMSCs/mSS achieved satisfactory bone mineral densities (BMD) at 12 months post-operation close to those of normal mandible (p>0.05). The quantities of newly formed bone area for the bMSCs/mSS group was higher than the bMSCs/SS group (p<0.01), but no significant differences were found when compared with the autograft group (p>0.05). In contrast, bony defects remained in the center with undegraded silk fibroin scaffold and fibrous connective tissue, and new bone only formed at the periphery in the groups treated with mSS or SS alone. The results suggested that apatite-coated silk fibroin scaffolds combined with bMSCs could be successfully used to repair mandibular critical size border defects and the premineralization of these porous silk fibroin protein scaffolds provided an increased osteoconductive environment for bMSCs to regenerate sufficient new bone tissue.

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Dataset Information

Aesthetic Enhancement of the Gonial Angle and Inferior Mandibular Border in the Chinese Population.

Background

Objectives

Methods

Results

Conclusions

Publications

Aesthetic Enhancement of the Gonial Angle and Inferior Mandibular Border in the Chinese Population.

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