Carbapenemase genes distribution in clonal lineages of Acinetobacter baumannii: a comprehensive study on plasmids and chromosomes.

ABSTRACT:

Background

The global spread of plasmids carrying carbapenemase genes within carbapenem resistant Acinetobacter baumannii (CRAB) strains poses a worldwide public health issue. In this study, we conducted a comprehensive genetic analysis of plasmids and chromosomes harboring the major carbapenemase genes (bla _NDM, bla _KPC, bla _VIM, bla _IMP, bla _GES, bla _OXA-58-like, bla _OXA-24/40-like, bla _OXA-143-like, and bla _OXA-23-like) in CRAB strains using bioinformatic tools.

Methods

We retrieved plasmids and chromosomes carrying the major carbapenemase genes from GenBank. The size, replicon type, and conjugal apparatus

SUBMITTER: Beig M 

PROVIDER: S-EPMC10722191 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature