Effect of acute and long-term exercise on leptin levels in depressed outpatients.

ABSTRACT:

Background

Depression is a leading cause of disability worldwide and a significant contributor to the global burden of disease. Altered leptin levels are known to be associated with depressive symptoms, however discrepancies in the results of increased or decreased levels exist. Due to various limitations associated with commonly used antidepressant drugs, alternatives such as exercise therapy are gaining more importance. Therefore, the current study investigates whether depressed patients have higher leptin levels compared to healthy controls and if exercise is efficient to reduce these levels.

Methods

Leptin levels of 105 participants with major depressive disorder (MDD; 45.7% female, age mean ± SEM: 39.1 ± 1.0) and 34 healthy controls (HC; 61.8% female, age mean ± SEM: 36

SUBMITTER: Heinen D 

PROVIDER: S-EPMC10722655 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature