Hyperacute autonomic and cortical function recovery following cardiac arrest resuscitation in a rodent model.

ABSTRACT:

Objective

There is a complex interaction between nervous and cardiovascular systems, but sparse data exist on brain-heart electrophysiological responses to cardiac arrest resuscitation. Our aim was to investigate dynamic changes in autonomic and cortical function during hyperacute stage post-resuscitation.

Methods

Ten rats were resuscitated from 7-min cardiac arrest, as indicators of autonomic response, heart rate (HR), and its variability (HRV) were measured. HR was monitored through continuous electrocardiography, while HRV was assessed via spectral analysis, whereby the ratio of low-/high-frequency (LF/HF) power indicates the balance between sympathetic/parasympathetic activities. Cortical response was evaluated by continuous electroencephalography and quantitative analys

SUBMITTER: Guo Y 

PROVIDER: S-EPMC10723251 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature