RERconverge Expansion: Using Relative Evolutionary Rates to Study Complex Categorical Trait Evolution.

ABSTRACT: Comparative genomics approaches seek to associate evolutionary genetic changes with the evolution of phenotypes across a phylogeny. Many of these methods, including our evolutionary rates based method, RERconverge, lack the capability of analyzing non-ordinal, multicategorical traits. To address this limitation, we introduce an expansion to RERconverge that associates shifts in evolutionary rates with the convergent evolution of multi-categorical traits. The categorical RERconverge expansion includes methods for performing categorical ancestral state reconstruction, statistical tests for associating relative evolutionary rates with categorical variables, and a new method for performing phylogenetic permulations on multi-categorical traits. In addition to demonstrating our new method on a t

SUBMITTER: Redlich R 

PROVIDER: S-EPMC10723433 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature