Ontology highlight
ABSTRACT:
SUBMITTER: Liu X
PROVIDER: S-EPMC10724393 | biostudies-literature | 2023 Oct
REPOSITORIES: biostudies-literature
Liu Xin X Yan Chunli C Chang Chunxiao C Meng Fansong F Shen Wenjie W Wang Song S Zhang Yi Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 20231024 35
The forkhead box transcription factor A2 (FOXA2) is a transcription factor and plays a key role in embryonic development, metabolism homeostasis and tumor cell proliferation; however, its regulatory potential in CRC is not fully understood. Here, it is found that FOXA2 expression is markedly up-regulated in tumor samples of CRC patients as compared with the normal tissues, which is closely associated with the worse survival in patients with CRC. Notably, a positive correlation between FOXA2 and ...[more]