Evaluating the cost-effectiveness of [¹⁸F]FDG-PET/CT for investigation of persistent or recurrent neutropenic fever in high-risk haematology patients.

ABSTRACT:

Background

A recent randomised trial demonstrated [¹⁸F]fluorodeoxyglucose positron-emission tomography in combination with low-dose CT (FDG-PET/CT), compared to standard of care computed tomography (CT) imaging, positively impacted antimicrobial management and outcomes of acute leukaemia and haematopoietic stem cell transplant recipients with persistent and recurrent neutropenic fever. We conducted an economic evaluation from a healthcare perspective alongside the clinical trial.

Methods

Unit costs in Australian dollars were applied to all resources used (antimicrobials, diagnostic tests, ICU and hospital bed days). Effectiveness was measured as number of patients with antimicrobial rationalisation, 6-month mortality and quality-adjusted life years (QALYs) derived

SUBMITTER: Tew M 

PROVIDER: S-EPMC10724891 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature