Association between selective digestive decontamination and decreased rate of acquired candidemia in mechanically ventilated ICU patients: a multicenter nationwide study.

ABSTRACT:

Background

Candidemia is a high-risk complication among intensive care unit (ICU) patients. While selective digestive decontamination (SDD) has been shown to be effective in preventing ICU-acquired bacterial secondary infection, its effects on ICU-acquired candidemia (ICAC) remain poorly explored. Therefore, we sought to assess the effects of SDD on ICAC.

Method

Using the REA-REZO network, we included adult patients receiving mechanical ventilation for at least 48 h from January 2017 to January 2023. Non-parsimonious propensity score matching with a 1:1 ratio was performed to investigate the association between SDD and the rate of ICAC.

Results

A total of 94 437 patients receiving at least 48 h of mechanical ventilation were included throughout the study period. Of th

SUBMITTER: Reizine F 

PROVIDER: S-EPMC10724923 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature