The predictive validity of a Brain Care Score for dementia and stroke: data from the UK Biobank cohort.

ABSTRACT:

Introduction

The 21-point Brain Care Score (BCS) was developed through a modified Delphi process in partnership with practitioners and patients to promote behavior changes and lifestyle choices in order to sustainably reduce the risk of dementia and stroke. We aimed to assess the associations of the BCS with risk of incident dementia and stroke.

Methods

The BCS was derived from the United Kingdom Biobank (UKB) baseline evaluation for participants aged 40-69 years, recruited between 2006-2010. Associations of BCS and risk of subsequent incident dementia and stroke were estimated using Cox proportional hazard regressions, adjusted for sex assigned at birth and stratified by age groups at baseline.

Results

The BCS (median: 12; IQR:11-14) was derived for 398,990 UKB parti

SUBMITTER: Singh SD 

PROVIDER: S-EPMC10725202 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature