The Circassians and the Chechens in Jordan: results of a decade of epidemiological and genetic studies.

ABSTRACT: Circassians and Chechens in Jordan, both with Caucasian ancestry, are genetically isolated due to high rate of endogamous marriages. Recent interest in these populations has led to studies on their genetic similarities, differences, and epidemiological differences in various diseases. Research has explored their predisposition to conditions like diabetes, hypertension, and cancer. Moreover, pharmacogenetic (PGx) studies have also investigated medication response variations within these populations, and forensic studies have further contributed to understanding these populations. In this review article, we first discuss the background of these minority groups. We then show the results of a principle component analysis (PCA) to investigate the genetic relationships between Circassian and Che

SUBMITTER: Abudahab S 

PROVIDER: S-EPMC10725377 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature