Surface plasmon coupling between wide-field SPR microscopy and gold nanoparticles.

ABSTRACT: The coupling behavior of the wide field surface plasmon microscopy (WF-SPRM) with single-, two-, and multiple-gold nanoparticles (AuNPs) with different AuNPs sizes is investigated using theoretical, simulation, and experimental approaches. The signal intensity of a single AuNP increases from 208 a.u. to 583 a.u. as particle size increases from 40 to 80 nm, which evidences the signal-building mechanism of Rayleigh scattering theory. A discrete particle model of SPR is used to understand the interaction between an Au-layer and a single AuNP. The calculated intensity profile of the single AuNP from the discrete particle model is accepted with the experimental data. In addition, the superposition between 2-AuNPs surface plasmon waves is studied using the finite element method as well as experi

SUBMITTER: Al-Bataineh QM 

PROVIDER: S-EPMC10725443 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature