Risk Calculation in the Medication Arm of the Ocular Hypertension Treatment Study.

ABSTRACT:

Purpose

Risk assessment is integral to the management of individuals with ocular hypertension (OHTN). This study aims to determine the predictive accuracy of the Ocular Hypertension Treatment Study 5-year risk calculator (OHTS calculator) among treated patients with OHTN by applying it to patients randomized to the Ocular Hypertension Treatment Study (OHTS) medication arm.

Design

Post hoc secondary analysis of a randomized clinical trial.

Subjects

Individuals participating in the OHTS who were randomized to the medication arm. Only participants with complete baseline data in both eyes were included (n = 726).

Methods

The hazard ratios (HRs) of the medication group in OHTS were compared to the HR used for the OHTS calculator using the z-test statistic to establi

SUBMITTER: Leshno A 

PROVIDER: S-EPMC10725513 | biostudies-literature | 2023 Nov-Dec

REPOSITORIES: biostudies-literature