Comparison of photon intensity modulated, hybrid and volumetric modulated arc radiation treatment techniques in locally advanced non-small cell lung cancer.

ABSTRACT:

Background and purpose

There is no consensus on the best photon radiation technique for non-small cell lung cancer (NSCLC). This study quantified the differences between commonly used treatment techniques in NSCLC to find the optimal technique.

Materials and methods

Treatment plans were retrospectively generated according to clinical guidelines for 26 stage III NSCLC patients using intensity modulated radiation therapy (IMRT), hybrid, and volumetric modulated arc therapy (VMAT_C, and VMAT_V5 optimized for lower lung and heart dose). Plans were evaluated for target coverage, organs at risk dose (including heart substructures) and normal tissue complication probabilities (NTCP).

Results

The comparison showed significant and largest median differences

SUBMITTER: Hattu D 

PROVIDER: S-EPMC10726236 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature