Evolution of the Spider Homeobox Gene Repertoire by Tandem and Whole Genome Duplication.

ABSTRACT: Gene duplication generates new genetic material that can contribute to the evolution of gene regulatory networks and phenotypes. Duplicated genes can undergo subfunctionalization to partition ancestral functions and/or neofunctionalization to assume a new function. We previously found there had been a whole genome duplication (WGD) in an ancestor of arachnopulmonates, the lineage including spiders and scorpions but excluding other arachnids like mites, ticks, and harvestmen. This WGD was evidenced by many duplicated homeobox genes, including two Hox clusters, in spiders. However, it was unclear which homeobox paralogues originated by WGD versus smaller-scale events such as tandem duplications. Understanding this is a key to determining the contribution of the WGD to arachnopulmonate genome

SUBMITTER: Aase-Remedios ME 

PROVIDER: S-EPMC10726417 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature