Preoperative assessment of retroperitoneal Liposarcoma using volume-based ¹⁸F-FDG PET/CT: implications for surgical strategy and prognosis.

ABSTRACT:

Purpose

Retroperitoneal liposarcoma (RLPS) poses a challenging scenario for surgeons due to its unpredictable biological behavior. Surgery remains the primary curative option for RLPS; however, the need for additional information to guide surgical strategies persists. Volume-based ¹⁸F-FDG PET/CT may solve this issue.

Methods

We analyzed data from 89 RLPS patients, measuring metabolic tumor volume (MTV), total lesion glycolysis (TLG), and maximum standardized uptake value (SUVmax) and explored their associations with clinical, prognostic, and pathological factors.

Results

MTV, TLG of multifocal and recurrent RLPS were significantly higher than unifocal and primary ones (P < 0.001, P < 0.001, P = 0.003 and P = 0.002, respectively). SUVmax correlated with FNCL

SUBMITTER: Liu DN 

PROVIDER: S-EPMC10726537 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature