TCGAplot: an R package for integrative pan-cancer analysis and visualization of TCGA multi-omics data.

ABSTRACT:

Background

Pan-cancer analysis examines both the commonalities and heterogeneity among genomic and cellular alterations across numerous types of tumors. Pan-cancer analysis of gene expression, tumor mutational burden (TMB), microsatellite instability (MSI), and tumor immune microenvironment (TIME), and methylation becomes available based on the multi-omics data from The Cancer Genome Atlas Program (TCGA). Some online tools provide analysis of gene and protein expression, mutation, methylation, and survival for TCGA data. However, these online tools were either Uni-functional or were not able to perform analysis of user-defined functions. Therefore, we created the TCGAplot R package to facilitate perform pan-cancer analysis and visualization of the built-in multi-omic TCGA data.

SUBMITTER: Liao C 

PROVIDER: S-EPMC10726608 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature