Predictive models of long-term survival outcomes following radical cystectomy.

ABSTRACT:

Background

Identifying the likelihood of life-threatening recurrence after radical cystectomy by reliable and user-friendly predictive models remains an unmet need in the clinical management of invasive bladder cancer.

Methods

A total of 204 consecutive patients undergoing open radical cystectomy (ORC) for bladder cancer were retrospectively enrolled between May 2005 and August 2020. Clinicopathological and peri-ORC therapeutic data were extracted from clinical records. We explored predictive factors that significantly affected the primary endpoint of overall survival (OS) and secondary endpoints of cancer-specific survival (CSS) and recurrence-free survival (RFS).

Results

During a median follow-up of 3.9 years, 42 (20.6%) and 10 (4.9%) patients died due to bladder ca

SUBMITTER: Ohtsu A 

PROVIDER: S-EPMC10726758 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature