Association between salivary mature brain-derived neurotrophic factor and psychological distress in healthcare workers.

ABSTRACT:

Introduction

Previous studies have suggested association between brain-derived neurotrophic factor (BDNF) and the stress level of workers. However, no studies have investigated the potential of salivary mature BDNF (mBDNF) level as a noninvasive biomarker for psychological distress. This study aimed to explore the reliability of salivary mBDNF as a biomarker for psychological distress in healthcare workers. Furthermore, we examined the relationship between salivary and plasma mBDNF levels and their correlation with age, sex, body mass index (BMI), and exercise habits.

Methods

Fifty-one healthy healthcare workers (26 men) from the University of Occupational and Environmental Health, Japan, participated in this study. In this cross-sectional study, participants provided demogr

SUBMITTER: Ikenouchi A 

PROVIDER: S-EPMC10726813 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature