Association of Life's Essential 8 With Cardiovascular Disease and Mortality: The Framingham Heart Study.

ABSTRACT:

Background

The association of the American Heart Association's updated cardiovascular health score, the Life's Essential 8 (LE8), with cardiovascular disease (CVD) and death is not described in the FHS (Framingham Heart Study).

Methods and results

We evaluated Framingham Offspring participants at examinations 2 and 6 (n=2888 and 1667; and mean age, 44 and 57 years, respectively), free of CVD with information on LE8 components. Using age-sex-adjusted Cox models, we related LE8 and its change (examination 2 to examination 6) with CVD and death risk and compared associations with those of the Life's Simple 7 score. Mean LE8 score at examination 2 was 67 points (minimum, 26 points; maximum, 100 points). At both examinations, participants were reclassified to a different cardiova

SUBMITTER: Rempakos A 

PROVIDER: S-EPMC10727315 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature