Initiation of opioid agonist therapy after hospital visits for opioid poisonings in Ontario.

ABSTRACT:

Background

Emergency department visits and hospital admissions for opioid toxicity are opportunities to initiate opioid agonist therapy (OAT), which reduces morbidity and mortality in patients with opioid use disorder (OUD). The study objectives were to evaluate OAT initiation rates after a hospital encounter for opioid toxicity in Ontario, Canada, and determine whether publication of a 2018 Canadian OUD management guideline was associated with increased initiation.

Methods

We conducted a retrospective, population-based serial cross-sectional study of hospital encounters for opioid toxicity among patients with OUD between Jan. 1, 2013, and Mar. 31, 2020, in Ontario, Canada. The primary outcome was OAT initiation (methadone, buprenorphine-naloxone, or slow-release oral morphi

SUBMITTER: Hu T 

PROVIDER: S-EPMC10727793 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature