Effects of aminophylline therapy on urine output and kidney function in children with acute kidney injury.

ABSTRACT:

Background

Acute kidney injury (AKI) is a frequent complication of children admitted to the paediatric intensive care unit. One key management modality of AKI is the use of diuretics to reduce fluid overload. Aminophylline, a drug that is well known for its use in the treatment of bronchial asthma, is also purported to have diuretic effects on the kidneys. This retrospective cohort study assesses the effect of aminophylline in critically ill children with AKI.

Methods

A retrospective chart review of children admitted to the paediatric intensive care unit of the Red Cross War Memorial Children's Hospital (RCWMCH) with AKI who received aminophylline (from 2012 to June 2018) was carried out. Data captured and analyzed included demographics, underlying disease conditions, medica

SUBMITTER: Nyann BI 

PROVIDER: S-EPMC10728232 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature