Polysubstance use and post-discharge mortality risk among hospitalized patients with opioid use disorder.

ABSTRACT: Polysubstance use is becoming increasingly common and presents several harms. This study aimed to examine the association of comorbid cocaine, alcohol (binge drinking), and sedative use with mortality among hospitalized patients with opioid use disorder (OUD). A subsample of adult medical/surgical hospital patients with OUD who were seen by a hospital addiction consultation service in Baltimore City and enrolled in a randomized trial of a patient navigation intervention were included in this study (N = 314; 45 % female; 48 % White; mean age = 44). Death certificate data from the Maryland Division of Vital Records was used, covering 3.3-5.5 years post-discharge. Multivariable proportional hazards Cox regression and competing risks regression were used to estimate all-cause mortality

SUBMITTER: Hochstatter KR 

PROVIDER: S-EPMC10728463 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature