Genetic components of Escherichia coli involved in its complex prey-predator interaction with Myxococcus xanthus.

ABSTRACT: Myxococcus xanthus and Escherichia coli represent a well-studied microbial predator-prey pair frequently examined in laboratory settings. While significant progress has been made in comprehending the mechanisms governing M. xanthus predation, various aspects of the response and defensive mechanisms of E. coli as prey remain elusive. In this study, the E. coli MG1655 large-scale chromosome deletion library was screened, and a mutant designated as ME5012 was identified to possess significantly reduced susceptibility to predation by M. xanthus. Within the deleted region of ME5012 encompassing seven genes, the significance of dusB and fis genes in driving the observed phenotype became apparent. Specifically, the deletion of fis res

SUBMITTER: Zhang N 

PROVIDER: S-EPMC10728724 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature