Local Treatment and Treatment-Related Adverse Effects Among Patients With Advanced Prostate Cancer.

ABSTRACT:

Importance

Recent data suggest that local treatment with radical prostatectomy or radiation may improve survival outcomes in men with advanced prostate cancer. However, evidence is lacking on treatment-related adverse effects among men with advanced prostate cancer.

Objective

To assess the association of local treatment on treatment-related adverse effects among men diagnosed with advanced prostate cancer.

Design, setting, and participants

This cohort study assessed men diagnosed with advanced prostate cancer (defined as T4, N1, and/or M1 prostate cancer) between January 1, 1999, and December 31, 2013, with follow-up through December 31, 2021, who were treated at Veterans Health Administration medical centers.

Exposure

Local treatment with radical prostatectomy

SUBMITTER: Khan S 

PROVIDER: S-EPMC10728764 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature