Incidence of Colorectal Cancer in Patients Diagnosed With Pyogenic Liver Abscess.

ABSTRACT:

Importance

Colorectal cancer (CRC) can compromise the mucosal barrier and subsequently allow a route for bacterial invasion into the portal system or systemic circulation. Despite preliminary data suggesting that patients who experienced pyogenic liver abscess (PLA) have higher CRC incidence rates, data from outside the Southeast Asian population are sparse.

Objective

To investigate whether there is an association between PLA and the subsequent incidence of diagnosed CRC using the Veterans Health Administration (VHA) cohort.

Design, setting, and participants

A patient-level matched retrospective cohort study was conducted at 127 VHA hospitals across the US from January 1, 2003, to December 31, 2020. Patients were followed up to 10 years from PLA diagnosis. Data analys

SUBMITTER: Suzuki H 

PROVIDER: S-EPMC10728768 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature