Identification of a GABAergic neuroblast lineage modulating sweet and bitter taste sensitivity.

ABSTRACT: In Drosophila melanogaster, processing of gustatory information and controlling feeding behavior are executed by neural circuits located in the subesophageal zone (SEZ) of the brain.¹ Gustatory receptor neurons (GRNs) project their axons in the primary gustatory center (PGC), which is located in the SEZ.^1,2,3,4 To address the function of the PGC, we need detailed information about the different classes of gustatory interneurons that frame the PGC. In this work, we screened large collections of driver lines for SEZ interneuron-specific labeling and subsequently used candidate lines to access the SEZ neuroblast lineages. We converted 130 Gal4 lines to LexA drivers and carried out functional screening usin

SUBMITTER: Zhao Y 

PROVIDER: S-EPMC10728805 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature