Altered dynamical integration/segregation balance during anesthesia-induced loss of consciousness.

ABSTRACT: In recent years, brain imaging studies have begun to shed light on the neural correlates of physiologically-reversible altered states of consciousness such as deep sleep, anesthesia, and psychedelic experiences. The emerging consensus is that normal waking consciousness requires the exploration of a dynamical repertoire enabling both global integration i.e., long-distance interactions between brain regions, and segregation, i.e., local processing in functionally specialized clusters. Altered states of consciousness have notably been characterized by a tipping of the integration/segregation balance away from this equilibrium. Historically, functional MRI (fMRI) has been the modality of choice for such investigations. However, fMRI does not enable characterization of the integration/segregat

SUBMITTER: Lord LD 

PROVIDER: S-EPMC10728865 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature