NcRNAs: an unexplored cellular defense mechanism in leprosy.

ABSTRACT: Leprosy is an infectious disease primarily caused by the obligate intracellular parasite Mycobacterium leprae. Although it has been considered eradicated in many countries, leprosy continues to be a health issue in developing nations. Besides the social stigma associated with it, individuals affected by leprosy may experience nerve damage leading to physical disabilities if the disease is not properly treated or early diagnosed. Leprosy is recognized as a complex disease wherein socioenvironmental factors, immune response, and host genetics interact to contribute to its development. Recently, a new field of study called epigenetics has emerged, revealing that the immune response and other mechanisms related to infectious diseases can be influenced by noncoding RNAs. This review aims

SUBMITTER: Santana-da-Silva MN 

PROVIDER: S-EPMC10729009 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature