Independent and joint associations of cardiorespiratory fitness and BMI with dementia risk: the Cooper Center Longitudinal Study.

ABSTRACT:

Objective

This study aimed to examine the association of midlife fitness and body mass index (BMI) with incident dementia later in life.

Design and participants

A cohort study of 6428 individuals (mean age 50.9±7.6 years) from the Cooper Center Longitudinal Study.

Measures

Cardiorespiratory fitness and BMI were assessed twice (1970-1999) during visits to the Cooper Clinic, a preventive medicine clinic in Dallas, Texas. These measures were examined as continuous and categorical variables. As continuous variables, fitness and BMI were examined at baseline (averaged of two examinations) and as absolute change between exams (mean time 2.1±1.8 years). Variables were categorised: unfit versus fit and normal versus overweight/obese. Medicare claims data were used to obtain a

SUBMITTER: Gafni T 

PROVIDER: S-EPMC10729062 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature