Non-specific effects of Pneumococcal and Haemophilus vaccines in children aged 5 years and under: a systematic review.

ABSTRACT:

Objective

To determine the evidence for non-specific effects of the Pneumococcal and Haemophilus influenza vaccine in children aged 5 years and under.

Data sources

A key word literature search of MEDLINE, EMBASE, The Cochrane Central Register of Controlled Trials, the European Union Clinical Trials Register and ClinicalTrials.gov up to June 2023.

Study eligibility criteria

Randomised controlled trials (RCTs), quasi-RCT or cohort studies.

Participants

Children aged 5 or under.

Study appraisal and synthesis methods

Studies were independently screened by two reviewers, with a third where disagreement arose. Risk of bias assessment was performed by one reviewer and confirmed by a second. Results were tabulated and a narrative description performed.

Result

SUBMITTER: Geraghty K 

PROVIDER: S-EPMC10729116 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature