Predictive model for epileptogenic tubers from all tubers in patients with tuberous sclerosis complex based on ¹⁸F-FDG PET: an 8-year single-centre study.

ABSTRACT:

Background

More than half of patients with tuberous sclerosis complex (TSC) suffer from drug-resistant epilepsy (DRE), and resection surgery is the most effective way to control intractable epilepsy. Precise preoperative localization of epileptogenic tubers among all cortical tubers determines the surgical outcomes and patient prognosis. Models for preoperatively predicting epileptogenic tubers using ¹⁸F-FDG PET images are still lacking, however. We developed noninvasive predictive models for clinicians to predict the epileptogenic tubers and the outcome (seizure freedom or no seizure freedom) of cortical tubers based on ¹⁸F-FDG PET images.

Methods

Forty-three consecutive TSC patients with DRE were enrolled, and 235 cortical tubers were selected as the

SUBMITTER: Wang Z 

PROVIDER: S-EPMC10729377 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature