Toxocara canis-induced changes in host intestinal microbial communities.

ABSTRACT:

Background

Toxocara canis is a roundworm that resides in the gastrointestinal tract of dogs and causes various pathological changes. The dog's intestinal system consists of a diverse and dynamic bacterial community that has extensive effects on intestinal physiology, immunity and metabolics. In the case of intestinal parasites, interactions with the host intestinal flora are inevitable during the process of parasitism.

Methods

We studied the role of T. canis in regulating the composition and diversity of the intestinal flora of the host by high-throughput sequencing of the 16S ribosomal RNA gene and various bioinformatics analyses.

Results

The α-diversity analysis showed that Toxocara canis infection resulted in a significant decrease in the abundance and diversity of

SUBMITTER: Sieng S 

PROVIDER: S-EPMC10729416 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature