Microbiological profile of patients treated for postoperative peritonitis: temporal trends 1999-2019.

ABSTRACT:

Background

Temporal changes in the microbiological resistance profile have been reported in several life-threatening infections. However, no data have ever assessed this issue in postoperative peritonitis (POP). Our purpose was to assess the rate of multidrug-resistant organisms (MDROs) in POP over a two-decade period and to analyse their influence on the adequacy of empirical antibiotic therapy (EAT).

Methods

This retrospective monocentric analysis (1999-2019) addressed the changes over time in microbiologic data, including the emergence of MDROs and the adequacy of EAT for all intensive care unit adult patients treated for POP. The in vitro activities of 10 antibiotics were assessed to determine the most adequate EAT in the largest number of cases among 17 antibiotic regim

SUBMITTER: Montravers P 

PROVIDER: S-EPMC10729506 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature