The clinical differentiation of blood culture-positive and -negative sepsis in burn patients: a retrospective cohort study.

ABSTRACT:

Background

Sepsis is a potentially life-threatening condition that occurs when the body's response to infection leads to widespread inflammation and tissue damage. Negative cultures can make it difficult for clinicians to make a diagnosis and may raise questions about the validity of the definition of sepsis. In addition, the clinical distinctions between burn patients with blood culture-positive and -negative sepsis are also poorly understood. Therefore, this study aimed to examine the clinical differences between blood culture-positive and -negative sepsis in burn patients in order to improve the understanding of the pathophysiology and epidemiology of sepsis in this population.

Methods

This study had a retrospective design, and the participants were adults aged ≥18 years.

SUBMITTER: Yoon J 

PROVIDER: S-EPMC10729782 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature