Towards better antivenoms: navigating the road to new types of snakebite envenoming therapies.

ABSTRACT: Snakebite envenoming is a significant global health challenge, and for over a century, traditional plasma-derived antivenoms from hyperimmunized animals have been the primary treatment against this infliction. However, these antivenoms have several inherent limitations, including the risk of causing adverse reactions when administered to patients, batch-to-batch variation, and high production costs. To address these issues and improve treatment outcomes, the development of new types of antivenoms is crucial. During this development, key aspects such as improved clinical efficacy, enhanced safety profiles, and greater affordability should be in focus. To achieve these goals, modern biotechnological methods can be applied to the discovery and development of therapeutic agents that can neutra

SUBMITTER: Thumtecho S 

PROVIDER: S-EPMC10729942 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature