Phylogeographic characterization of Burkholderia pseudomallei isolated from Bangladesh.

ABSTRACT:

Background

Burkholderia pseudomallei possesses a diverse set of genes which encode a vast array of biological functions reflecting its clinical, ecological and phenotypic diversity. Strain variation is linked to geographic location as well as pattern of land uses. This soil-dwelling Gram-negative pathogen causes melioidosis, a tropical disease endemic in northern Australia and Southeast Asian regions including Bangladesh. Phylogeographic analyses of B. pseudomallei isolates by molecular typing techniques could be used to examine the diversity of this organism as well as to track melioidosis epidemics.

Methods

In this study, 22 B. pseudomallei isolates, of which 20 clinical and two soil isolates were analyzed, utilizing Real-time PCR assay and multilocus sequence typing (MLST

SUBMITTER: Jilani MSA 

PROVIDER: S-EPMC10729972 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature