Neurophysiological error processing and addiction self-awareness correlates of reduced insight in cannabis use disorder.

ABSTRACT:

Background and aims

Cannabis use disorder (CUD) prevalence has increased, while perceived risks of cannabis use and CUD treatment need have decreased. Chronic cannabis use may also impair the neural and behavioral mechanisms of insight, further hampering treatment-seeking. This study aimed to measure whether CUD is characterized by reduced self-monitoring in drug-related contexts (objectively-assessed insight), subserved by functional neural abnormalities in error-processing and manifested clinically as decreased awareness of the need to change.

Design

Case-control laboratory study was used.

Setting

University setting was in Alabama, USA.

Participants

There were 42 CUD participants and 47 age-, sex-, and nicotine use-matched controls.

Measurements

Partic

SUBMITTER: Macatee RJ 

PROVIDER: S-EPMC10730014 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature