Functional profiling of gut microbial and immune responses toward different types of dietary fiber: a step toward personalized dietary interventions.

ABSTRACT: Dietary fiber plays a crucial role in maintaining gut and overall health. The objective of this study was to investigate whether different types of dietary fiber elicited specific changes in gut microbiota composition and the production of short-chain fatty acids. To test this, a longitudinal crossover study design was employed, in which healthy adult women consumed three distinct dietary fiber supplements: Inulin (fructo-oligosaccharide), Vitafiber (isomalto-oligosaccharide), and Fibremax (mixture of different fiber) during a one-week intervention period, followed by a 2-week washout period. A total of 15 g of soluble fiber was consumed daily for each supplement. Samples were collected before and after each intervention to analyze the composition of the gut microbiota by 16S rRNA sequenci

SUBMITTER: Tan J 

PROVIDER: S-EPMC10730188 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature