Association between IL10 rs1800896 polymorphism and risk of pediatric asthma: A meta-analysis.

ABSTRACT:

Introduction

Asthma is a common chronic condition in children. Several studies have explored the potential association between IL10 rs1800896 polymorphism and the risk of asthma in children, but the findings have been inconsistent. To address these discrepancies, we conducted a systematic review and meta-analysis to assess the relationship between IL10 rs1800896 polymorphisms and the susceptibility to pediatric asthma.

Methods

A literature search was conducted in PubMed, Scopus, Web of Science, and CNKI databases to identify eligible studies through April 2022. Meta-analysis was then performed using five genetic models: dominant, recessive, homozygous, heterozygous, and allele.

Results

A total of 12 studies comprising 1645 cases along with 1447 controls were included

SUBMITTER: Zhou Z 

PROVIDER: S-EPMC10730469 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature