Trends and patterns of antiseizure medication prescribing during pregnancy between 1995 and 2018 in the United Kingdom: A cohort study.

ABSTRACT:

Objective

To examine antiseizure medication (ASM) prescription during pregnancy.

Design

Population-based drug utilisation study.

Setting

UK primary and secondary care data, 1995-2018, from the Clinical Practice Research Datalink GOLD version.

Population or sample

752 112 completed pregnancies among women registered for a minimum of 12 months with an 'up to standard' general practice prior to the estimated start of pregnancy and for the duration of their pregnancy.

Methods

We described ASM prescription across the study period, overall and by ASM indication, examined patterns of prescription during pregnancy including continuous prescription and discontinuation, and used logistic regression to investigate factors associated with those ASM prescription patt

SUBMITTER: Madley-Dowd P 

PROVIDER: S-EPMC10730765 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature