Depression, antidepressant use, and the risk of type 2 diabetes: a nationally representative cohort study.

ABSTRACT:

Background

Previous studies have reported that depression can increase the risk of type 2 diabetes. However, they did not sufficiently consider antidepressants or comorbidity.

Methods

The National Health Insurance Sharing Service database was used. Among the sample population, 276,048 subjects who had been diagnosed with depression and prescribed antidepressants (DEP with antidepressants group) and 79,119 subjects who had been diagnosed with depression but not prescribed antidepressants (DEP without antidepressants group) were found to be eligible for this study. Healthy controls (HCs) were 1:1 matched with the DEP with antidepressants group for age and sex. We followed up with them for the occurrence of type 2 diabetes.

Results

In the group of DEP with antidepressant

SUBMITTER: Kim H 

PROVIDER: S-EPMC10731300 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature