Novel cuproptosis-related lncRNAs can predict the prognosis of patients with multiple myeloma.

ABSTRACT:

Background

Cuproptosis-related long-stranded non-coding RNAs (lncRNAs) have several implications for the prognosis of multiple myeloma (MM). This research aimed to construct a prognostic risk model for MM patients and explore the potential signaling pathways in the risk group.

Methods

Cuproptosis-related lncRNAs were obtained from the co-expression analysis of cuproptosis-related genes and lncRNAs. Subsequently, twelve cuproptosis-related lncRNAs were selected to construct a prognostic risk model of MM patients by the least absolute shrinkage and selection operator (LASSO) regression. Then, the clinical data of these patients were randomly divided into the training group and the testing group. Next, patients were divided into the low- and high-risk groups according to the me

SUBMITTER: Chen Y 

PROVIDER: S-EPMC10731335 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature