Development and validation of a nomogram for predicting the overall survival in non-small cell lung cancer patients with liver metastasis.

ABSTRACT:

Background

Among all metastatic lesions in non-small cell lung cancer (NSCLC), liver metastasis (LM) is the most lethal site with a median survival of less than 5 months. Few studies exclusively report on prognostic factors for these unique patients. We aimed to construct and validate a practical model to predict the prognosis of NSCLC patients with LM.

Methods

Cases of NSCLC with LM diagnosed between 2010 and 2015 were collected from the Surveillance, Epidemiology, and End Results (SEER) database, and were randomly split into training and validation cohort (7:3). The overall survival (OS) was measured from diagnosis until date of death or last follow-up. Cox regression analyses were performed to identify potential predictors of the model. A nomogram incorporating those inde

SUBMITTER: Xu T 

PROVIDER: S-EPMC10731345 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature