Effect of statins on hearing outcome in patients with idiopathic sudden sensorineural hearing loss.

ABSTRACT:

Objective

Statins have been reported to improve vascular endothelial function and microcirculation, reduce oxidative stress, and exert anti-inflammatory and protective effects against inner ear damage. Therefore, this study aimed to investigate the effect of statins on hearing prognosis in patients with idiopathic sudden sensorineural hearing loss (ISSNHL).

Methods

We reviewed the medical records of 149 patients diagnosed with ISSNHL. Clinical characteristics, hearing thresholds, statin medications, and hematological findings were investigated. First, patients with ISSNHL were assigned to the good and poor outcome groups, and factors influencing their prognosis were analyzed. Furthermore, patients with dyslipidemia were investigated to determine whether statins have therapeu

SUBMITTER: Nitta Y 

PROVIDER: S-EPMC10731490 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature