Highly hydrophilic and dispersed TiO₂ nano-system with enhanced photocatalytic antibacterial activities and accelerated tissue regeneration under visible light.

ABSTRACT: Titanium dioxide (TiO₂)-based photodynamic antibacterial (PDA) agents present a novel approach for addressing drug-resistant bacterial infections and the associated tissue damage. However, the suboptimal dispersibility, negative charge, and weak photocatalytic activity under visible light of TiO₂ hinder its practical applications. This study aimed to address these limitations by developing a highly hydrophilic and dispersed Zn-TiO₂/reduced graphene oxide (rGO) (HTGZ) nano-system with exceptional visible light catalytic activity and tissue repair ability. HTGZ produced an antibacterial ratio over 98% within a short time, likely due to the enhanced production of reactive oxygen species under visible light. After being co-cultured for 4 days, L929 cells and BM

SUBMITTER: Lu B 

PROVIDER: S-EPMC10731761 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature